Clinical Blogs — hyperpigmentation

When it comes to ingredients with strong supporting clinical data and variety of uses, vitamin B3 (niacinamide) is the one that is on the top of the list. It is one of the most versatile ingredients can be used in various skincare formulation with multiple benefits as a nutraceutical for our skin. Vitamin B3 is a multitask ingredient beneficial to skin health: Increases hydration: It strengthens the top layer of our skin (strata corneum) which is responsible for transdermal epidermal water loss (TEWL). B3 possesses antipruritic effect: enhances skin barrier protection by stimulating ceramide synthesis and stabilizing mast cells that...

Hyperpigmentation is a condition where areas of skin are darker in color as compared to the surrounding area of the skin. Major causes of hyperpigmentation are sun damage, scarring after inflammation of the skin (e.g acne, dermatitis, eczema), hormonal changes (melasma), drug-induced or disease related. Sun protection is a ‘must’ to prevent hyperpigmentation. In regards to treatment, hydroquinone still remains an important role. Hydroquinone (HQ) is a skin bleaching agent that inhibits the production of melanin which gives the skin its color. Recent studies have raised some question about its safety but it is considered as safe for short-term use...